| Team | Player | POS | Status | Injury | Out For | Expected Return |
|---|---|---|---|---|---|---|
 Blues |  Erik Gustafsson | D | Sidelined | Left Leg Injury | Day-to-Day | 2026-04-05 |
| Blues |  Stuart Skinner | G | Injured Reserve | Exhaustion | 3 Weeks | 2026-04-18 |
 Canadiens |  Juuse Saros | G | Injured Reserve | Exhaustion | 3 Weeks | 2026-04-18 |
 Ducks |  Alex Nedeljkovic | G | Injured Reserve | Exhaustion | 3 Weeks | 2026-04-18 |
 Flames |  Yaroslav Askarov | G | Sidelined | Exhaustion | Day-to-Day | 2026-04-03 |
 Golden Knights |  Joey Daccord | G | Injured Reserve | Exhaustion | 3 Weeks | 2026-04-18 |
 Kings |  Andrei Vasilevskiy | G | Injured Reserve | Exhaustion | 3 Weeks | 2026-04-18 |
 Lightning |  Sebastian Cossa | G | Injured Reserve | Exhaustion | 3 Weeks | 2026-04-18 |
 Mammoth |  Auston Matthews | C | Sidelined | Groin Injury | 1 Week | 2026-04-06 |
| Mammoth |  Dustin Wolf | G | Injured Reserve | Exhaustion | 3 Weeks | 2026-04-18 |
 Maple Leafs |  Joseph Woll | G | Injured Reserve | Exhaustion | 3 Weeks | 2026-04-18 |
 Oilers |  Ilya Sorokin | G | Injured Reserve | Exhaustion | 3 Weeks | 2026-04-18 |
 Penguins |  Sam Montembeault | G | Injured Reserve | Exhaustion | 3 Weeks | 2026-04-18 |
 Predators |  Alexandar Georgiev | G | Injured Reserve | Exhaustion | 3 Weeks | 2026-04-18 |
 Red Wings |  Kevin Bahl | D | Sidelined | Bruised Right Foot Injury | 1 Week | 2026-04-06 |
 Sabres |  Joel Eriksson Ek | C | Injured Reserve | Right Hip Injury | 1 Month | 2026-04-30 |
| Sabres |  Kevin Lankinen | G | Injured Reserve | Exhaustion | 3 Weeks | 2026-04-18 |
 Stars |  Matias Maccelli | LW/RW | Injured Reserve | Left Hand Injury | 2 Weeks | 2026-04-11 |
 Wild |  Jordan Binnington | G | Injured Reserve | Exhaustion | 3 Weeks | 2026-04-18 |