| Team | Player | POS | Status | Injury | Out For | Expected Return |
|---|---|---|---|---|---|---|
 Sabres |  Joel Eriksson Ek | C | Injured Reserve | Right Hip Injury | 1 Week | 2026-04-26 |
| Sabres |  Eric Comrie | G | Injured Reserve | Sprained Right Ankle Injury | 2 Weeks | 2026-05-03 |
 Sharks |  Josh Doan | RW | Injured Reserve | Bruised Right Shoulder Injury | 2 Weeks | 2026-04-30 |